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Omics International welcomes you to The 15th Indo Global Diabetes Summit & Medicare Expo to be held from November 21-23, 2016 in Hyderabad, India. The theme of Indo Diabetes Expo-2016 is “Emphasis on treatments and exploring diabetic complications.” Omics International organizes 1000+ Global events every year across the globe with support from 1000+ more scientific societies and Publishes 500 Open access journals which contains over 50000 eminent personalities, reputed scientists as editorial board members. The conference aims to provide opportunity and to share knowledge, expertise along with unparalleled networking opportunities between a large number of medical and industrial professionals in this sphere. Omics International Diabetic Medications conference gathers renowned scientists, physicians, surgeons, young researchers, industrial delegates and talented student communities in the field of diabetic medicine under a single roof where networking and global partnering happens for the acceleration of future research.
Diabetes has increasingly become a lifestyle-related disease as it afflicts young and old. As the number of patients grows across the globe, there has never been a stronger and more urgent need for novel therapeutic measures in clinical and preclinical evaluation, that arrest the growth of the disease. The diabetes market, consisting mainly of Type 1 and Type 2 diabetes, is large and growing significantly. The global market value for diabetes therapies and diagnostics has reached to $48.5 billion. The largest segment of the market, insulin products, is worth $20.8 billion in the recent times, including administration and diagnostic devices. Monitoring devices and other related equipment, the second-largest market is established with an investment of $13.5 billion in which was proposed for $11.3. The fastest-growing segment of oral hypoglycemic drugs manufacturing funding is $14.13 in present scenario of diabetes market.
Diabetes, often referred to by doctors as diabetes mellitus, describes a group of metabolic diseases in which the person has high blood glucose (blood sugar), either because insulin production is inadequate, or because the body's cells do not respond properly to insulin, or both. Patients with high blood sugar will typically experience frequent urination, they will become increasingly thirsty and hungry .The term diabetes mellitus describes several diseases of abnormal carbohydrate metabolism that are characterized by hyperglycemia. It is associated with a relative or absolute impairment in insulin secretion, along with varying degrees of peripheral resistance to the action of insulin. They are derived after doing many clinical trials on animal models. Every few years, the diabetes community reevaluates the current recommendations for the classification, diagnosis, and screening of diabetes, reflecting new information from research and clinical practice which in turns help in understanding current prevention and treatment options and cost effectiveness in treatment and prevention of Diabetes.
Track 2 Complications of Diabetes
People with type1 and type2 diabetes have an increased risk of developing a number of serious health problems. Consistently high blood glucose levels can lead to serious diseases affecting the Macro vascular (Coronary artery diseases, cardiomyopathy and stroke) and micro vascular (Retinopathy, neuropathy and nephropathy) complications. In addition, people with diabetes also have a higher risk of developing infections. In almost all high-income countries, diabetes is a leading cause of cardiovascular disease, blindness, kidney failure, and lower limb amputation. Maintaining blood glucose levels, blood pressure, and cholesterol at or close to normal can help delay or prevent diabetes complications. Hypoglycemia and Hyperglycemia are the other two factors are the two major complications of diabetes where hyperglycemia is an acute complication sharing many symptoms and hypoglycemia is an acute complication of several diabetes treatments.
The concept of 'new technologies' for type 1 diabetes and new discovery and emerging therapies in type 2 diabetes has expanded in recent years at a rate that some might consider comparable to 'Moore’s Law', and the sheer number of new technologies entering into the type 1 diabetes marketplace is also growing at a remarkable rate. From the patient’s perspective, this is not only exciting but can lead to a sense of optimism. Technologies that today are growing commonplace (e.g. insulin pumps, rapid HbA1c monitoring, etc come under new therapeutic mechanisms of diabetes. Indeed, it could be argued that the major advances in type 1 diabetes care made within the last quarter of a century have come from technology rather than biology. At the same time, not all new technologies succeed (e.g. the Glucowatch), regardless of their purported promise. Both type 1 diabetes patients and their healthcare providers will soon see a series of further advanced medical technologies used in hospital and new technologies and novel therapies in diabetes treatment whose basis is tied to the notion of improving the lives of those with the disease.
The main goal of diabetes management is, as far as possible, to restore carbohydrate metabolism to a normal state. To achieve this goal, individuals with an absolute deficiency of insulin require insulin replacement therapy, which is given through injections or an insulin pump. Insulin resistance, in contrast, can be corrected by dietary modifications and exercise. Other goals of diabetes management are to prevent or treat the many complications that can result from the disease itself and from its treatment. Healthy eating is a cornerstone of healthy living — with or without diabetes. But if you have diabetes, you need to know Impact of Food and Nutrition, impact of physical activity and yoga therapy in Diabetes Management. Diabetic foot complications result in huge costs for both society and the individual patients. Few reports on the health-economic consequences of diabetic foot infections have been published. Standards of medical care in Diabetes increased when compared to previous year.
Gastro paresis is a disorder affecting people with both type 1 and type 2 diabetes in which the stomach takes too long to empty its contents (delayed gastric emptying) Diabetic retinopathy is the most common diabetic eye disease and a leading cause of blindness in American adults. It is caused by changes in the blood vessels of the retina. Diabetic neuropathy is a type of nerve damage that can occur if you have diabetes. High blood sugar can injure nerve fibers throughout your body, but diabetic neuropathy most often damages nerves in your legs and feet. Currently, diabetic nephropathy is the leading cause of chronic kidney disease in the United States and other Western societies. It is also one of the most significant long-term complications in terms of morbidity and mortality for individual patients with diabetes. Diabetes is responsible for 30-40% of all end-stage renal disease (ESRD) cases in the United States.
Cardiomyopathy is a condition where the heart muscle is abnormal. The main types of cardiomyopathy include dilated, hypertrophic and restrictive cardiomyopathy. Cardiomyopathy makes it harder for your heart to pump and deliver blood to the rest of your body. Cardiomyopathy can lead to heart failure. Latent autoimmune diabetes in adults (LADA) is a disorder in which, despite the presence of islet antibodies at diagnosis of diabetes, the progression of autoimmune β-cell failure is slow.
Hypoglycemia is a medical emergency that involves an abnormally diminished content of glucose in the blood. Pregnant women who have never had diabetes before but who have high blood glucose (sugar) levels during pregnancy are said to have gestational diabetes. According to a 2014 analysis by the Centers for Disease Control and Prevention, the prevalence of gestational diabetes is as high as 9.2%. High blood pressure orhypertension increases the risk of heart disease and stroke. Hypertension risk factors include obesity, drinking too much alcohol, smoking, and family history. Beta-blockers are a common treatment for hypertension.
Diabetes is a common chronic disease that imposes considerable demands on the individual healthcare system. People with diabetes have a higher rate of cardiovascular disease than those without diabetes and are at increased risk for kidney failure, lower limb amputation and blindness. Obesity is a significant risk factor for diabetes and the prevalence of obesity in children and adults has dramatically increased in the past four decades. Diabetic dyslipidemia is one of the major risk factors for cardiovascular disease in diabetes mellitus. The characteristic features of diabetic dyslipidemia are a high plasma triglyceride concentration, low HDL cholesterol concentration and increased concentration of small dense LDL-cholesterol particles. In order to investigate the bioinformatics tools and methodologies used to in diabetes research, at first, this was difficult to do because it did not have a preconceived idea about how the research would be organized and how bioinformatics tools would be described or identified in the research. To get started, we ran several cursory searches using basic search terms such as bioinformatics and diabetes (research) through several databases to see what types of articles were returned. Diabesity can be defined as a metabolic dysfunction that ranges from mild blood sugar imbalance to full-fledged type 2 diabetes.
Endocrinology is the study of hormones and the treatment of hormone based diseases. The endocrine glands produce chemicals called hormones. These hormones are released into the blood stream and exert their action by stimulating other organs in the body. However, Clinical trials on endocrinology look at new ways to prevent, detect, or treat disease. The major endocrine glands are the thyroid, pancreas, parathyroid, adrenal, gonad and pituitary. The hormones from these glands regulate growth, metabolism, blood pressure, reproduction as well as many other necessary functions. Early Diagnosis and Treatment of Endocrine Disorders, written by a distinguished panel of clinical experts and research scientists, focuses on the early signs and symptoms of common endocrine diseases, surveys the clinical testing needed for a diagnosis, and concisely presents the best current recommendations for therapy. Pediatric endocrinology is a medical subspecialty that studies and treats conditions affecting physical growth and sexual development in children, as well as diabetes and other disorders of the endocrine (hormone) glands.
Weight control, diet and exercise play a critical role in controlling diabetes.Other options are:Insulin injections: Using a very thin needle, the patient injects insulin through the arm, leg or stomach wall every day.Oral drugs: Specific drugs can often lower blood sugar levels in people with type 2 diabetes by prompting the pancreas to release insulin and increasing its ability to work. Other types of oral drugs do not affect the release of insulin but increase the body's response to its own insulin.Without treatment diabetes insipidus can cause permanent kidney damage.Treatment usually consists of hormone replacement and treatment of any underlying cause (such as surgical removal of a pituitary tumor) that can be addressed.Non-hormone drugs may also be helpful, including:Diuretics,ADH-releasing drugs such as chlorpropamide, carbamazepine and clofibrate. These can reduce or eliminate the need for hormone replacement in some people who have a partial lack of vasopressin. These drugs are not effective, however, if a person has nephrogenic diabetes insipidus. Reducing the amount of salt consumed in the diet may also help.
Track 9 Biochemistry of Diabetes
Diabetes constitutes a major public health problem. Although substantial progress has been made in defining thegenetics of metabolic syndrome risk for specific subtypes of diabetes (e.g., maturity-onset diabetes of the young), the majority of genetic risk of diabetes (for type 1 and type 2) remain unresolved. This review focuses on the current knowledge of the genetic basis of diabetes and its complications, specifically diabetic nephropathy (DN), recent advances in genetics of diabetes, diabetes in ethnic groups, genetic lifestyle interactions andunderstanding the genetics of Diabetes. Ultimately, identification of genes that contribute to risk (or protection) of diabetes and its complications will allow identification of patients who have diabetes and are at risk and targeted treatment/interventional strategies.
Getting a new heart, liver, kidney, lung, or other organ can save your life. Sometimes, it can also lead to type 2 diabetes. Many people can stop taking steroids after 6 months or so. This may solve the problem. If scientists can develop safe immunosuppressant’s that always work, then many people with type 1 diabetes may choose to have pancreas transplants. Until then, many doctors think islet transplants are a better option even after performing clinical trials on islet transplants . Islets are clusters of cells in the pancreas that make insulin. In people with type 1 diabetes, islet cells are destroyed. Only 1-2% of the pancreas is made up of islet cells. Inpancreatic islet transplantation, cells are taken from a donor pancreas and transferred into another person. Once implanted, the new islets begin to make and release insulin. Researchers hope that islet transplantation will help people with type 1 diabetes live without daily injections of insulin. A transplant of the pancreas is usually reserved for those with serious complications. Pancreas transplants are most often done when a patient also receives a new kidney. The pancreas transplant adds little further risk in this situation and offers big benefits. However, transplant surgery is risky. Each person needs to carefully weigh the potential benefits and risks. Xenotransplantation for the treatment of type 1 diabetes is the transplantation of living cells, tissues or organs from one species to another. Such cells, tissues or organs are called xenografts or xenotransplants.